Food and mood: what the SMILES trial showed

Can what we eat affect depression? The first randomised trial of its kind showed that improving diet can help.

The Australian SMILES trial, published in BMC Medicine in 2017, included 67 adults with moderate to severe depression. Over 12 weeks, one group had seven sessions with a clinical dietitian, and the other had the same number of social support sessions. Depressive symptoms fell more in the diet group.

Remission results

After 12 weeks, remission, meaning near-complete disappearance of symptoms, was reached by 32% of the diet group and 8% of the control group. The trial is small, so it is important to confirm the results in larger studies.

What this means for you

  • More vegetables, fruit, legumes, wholegrains, fish and olive oil may also benefit your mood.
  • Diet is extra support, not a substitute for depression treatment.
  • If you want to change your diet, it is worth talking to a dietitian.

Sources

  • Jacka F. N., O’Neil A., Opie R. et al. (2017). A randomised controlled trial of dietary improvement for adults with major depression (the ‘SMILES’ trial). BMC Medicine, 15. doi:10.1186/s12916-017-0791-y

This article is for educational purposes and does not replace advice from a doctor.

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